Journal of ISSN: 2373-633XJCPCR

Cancer Prevention & Current Research
Case Report
Volume 3 Issue 1 - 2015
Electro-Chemotherapy in a Case of Oral Squamous Cell Carcinoma: Case Report and Considerations
Shanmughakumar1, Madullika1, Manohara Prasad E2 and Sasi Kumar S2*
1Govt General Hospital, India
2OnMed India Pvt Ltd., India
Received: January 26, 2015 | Published: July 28, 2015
*Corresponding author: Sasi Kumar S, OnMed India Pvt Ltd., No 243/8th Block, KKD Nagar, Chennai-118, India, Tel: 91-99140424174; Email:
Citation: Shanmughakumar , Madullika, Manohara PE, Sasi Kumar S (2015) Electro-Chemotherapy in a Case of Oral Squamous Cell Carcinoma: Case Report and Considerations. J Cancer Prev Curr Res 3(1): 00065. DOI: 10.15406/jcpcr.2015.03.00065

Abstract

Background: Squamous Cell Carcinoma (SCC) is the most common oral cavity malignant tumor. Surgery, radiotherapy, and chemotherapy have been major opinion for its treatment. ECT is a novel local treatment successfully used in secondary or primary skin or subcutaneous treatment.

Methods: we report a case of man affected by Squamous cell carcinoma male patient, aged 51 diagnosed with squamous cell carcinoma (SCC). Had pain, difficulty in swallowing and talking. Patient was treated with ECT with Eight, 1000V/cm, 100µs pulses were applied using Sennex electroporator. Results Two ECT sittings with 2 weeks interval were given and the tumor volume reduced significantly, enhancing the quality of life. Figure 1 shows the tumor, before and 12 days after treatment.

Figure 1: Head & Neck Cancer Patient 1 (before treatment (left), 12 days after treatment (right).

Conclusion: The Tumor volume reduced almost 90% shows good clinical results.

Background

Squamous Cell Carcinoma (SCC) is the most common oral cavity malignant tumor. Surgery, radiotherapy, and chemotherapy have been major opinion for its treatment. ECT is a novel local treatment successfully used in secondary or primary skin or subcutaneous treatment.

Methods

We report a case of man affected by Squamous cell carcinoma male patient, aged 51 diagnosed with squamous cell carcinoma (SCC). Had pain, difficulty in swallowing and talking. Patient was treated with ECT with Eight, 1000V/cm, 100µs pulses were applied using Sennex electroporator.

Results

Two ECT sittings with 2 weeks interval were given and the tumor volume reduced significantly, enhancing the quality of life. Figure 1 shows the tumor, before and 12 days after treatment.

Conclusion

The Tumor volume reduced almost 90% shows good clinical results [1-4].

References

  1. Kulkrni MK (2013) Head and neck cancer burden in India. Int J of Head and Neck Surgery 4(1): 29-35.
  2. Gehl J, Geertsen PF (2000) Efficient palliation of haemorrhaging malignant melanoma skin metastases by electrochemotherapy. Melanoma Res 10(6): 585-589.
  3. Campana LG, Mocellin S, Basso M, Puccetti O, De Salvo GL, et al. (2009) Bleomycin-based electrochemotherapy: clinical outcome from a single Institution’s experience with 52 patients. Ann Surg Oncol 16(1): 191-199.
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