International Journal of IJRRT

Radiology & Radiation Therapy
Opinion
Volume 1 Issue 2 - 2016
Von Meyenburg Complex
Renan Ibrahem Adam* and Heather Harris
Radiology Department, Nottingham University Hospitals, UK
Received: October 24, 2016| Published: December 19, 2016
*Corresponding author: Renan Ibrahem Adam, Radiology Department, Nottingham University Hospitals, Nottingham, NG7 2UH, United Kingdom, Tel: 0044(0)7931550973; Email:
Citation: Adam RI, Harris H (2016) Von Meyenburg Complex. Int J Radiol Radiat Ther 1(2): 00007. DOI: 10.15406/ijrrt.2016.01.00007

keywords: Hepatic; Abnormality; CT; Infection; Meyenburg complex; Hamartomas

Abbreviations

CT: Computed Tomography; ADPKD: Autosomal Dominant Polycystic Kidney Disease; MBH: Multiple Biliary Hamartomas

Opinion

A 63 years old female noted to have non-specific hepatic abnormality in a follow up chest CT for infection. The subsequent MRCP demonstrated numerous cystic lesions throughout the liver which showed no communication with the biliary tree (Figure 1). Diagnosis of Von Meyenburg Complex has been made. No further management or investigation is required.

Figure 1: Diagnosis of Von Meyenburg Complex.

Von Meyenburg Complex is a rare cause of multiple hepatic lesions, also known as multiple biliary hamartomas (MBH). It is named after pathologist called Hans von Meyenburg who was born in Dresden in 1887 and first described the pathology of multiple biliary hamartomas in 1918 [1].

MBH is asymptomatic condition and usually found incidentally at autopsy or on imaging with prevalence <1%. It is three times more common in women [2].

 The biliary hamartomas are consistent of small clusters of dilated cystic bile ducts which are not communicating with the biliary tree. On imaging, they appear as multiple small round or irregular lesions throughout the liver with peripheral predominance. No enhancement in the post contrast images [3]. The radiological differential diagnoses include multiple liver cysts and hepatic metastases.

Autosomal dominant polycystic kidney disease (ADPKD) and polycystic liver disease are known associations with this condition.

References

  1. Über DZ (1918) Beiträge zur pathologischen Anatomie und zur allgemeinen Pathologie. Jena 64: 477-532.
  2. Tohmé noun C, Cazals D, Noun R, Menassa L, Valla D, et al. (2008) Multiple biliary hamartomas: magnetic resonance features with histopathologic correlation. Eur Radiol 18(3): 493-499.
  3. Zheng RQ, Zhang B, Kudo M, Onda H, Inoue T (005) Imaging findings of biliary hamartomas. World J Gastroenterol 11(40): 6354-6359.
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